Overview of the Collection
Medical Heritage Center
Kapral, Frank A.
Frank A. Kapral Papers
17.0 linear feet
The Frank A. Kapral Papers (17 linear feet) contain laboratory notebooks and 35mm slides documenting Kapral’s research.
SPEC.202405.KAPRAL
The records are in English
English
1952-2004
Biography
Frank A. Kapral (1928-2022) was a professor in the Department of Molecular Virology, Immunology, and Medical Genetics at The Ohio State University. He was born in Philadelphia, Pennsylvania, and graduated from high school in Abington, Pennsylvania. In June 1946 Kapral enlisted in the U.S. Army and served for 18 months in the Army Medical Corps. He obtained his Bachelor of Science degree in bacteriology from the University of Science in Philadelphia (1952) and his Ph.D. in medical microbiology from the University of Pennsylvania (1956). After teaching at the University of Pennsylvania and working in research programs at the Veterans Administration Hospital in Philadelphia, and Philadelphia General Hospital, he moved to The Ohio State University and played a role in organizing the Department of Medical Microbiology for the University.
Kapral obtained the rank of full professor at Ohio State in 1969. In the fall of 1973, he was appointed acting chairman of the Department of Medical Microbiology and served in this role for five years. After retiring Kapral received the title of professor emeritus in July 1995 and continued to teach without compensation. In his career at The Ohio State University and the University of Pennsylvania it is estimated that he taught more than 8,000 medical students and mentored numerous graduate students. A particular research interest was studying diseases caused by staphylococcus aureus bacteria. His research made campus news in 1980 when he explained in an article for The Lantern that there was not a simple cure for toxic shock syndrome. Per Kapral, “Staphylococcus aureus produces a whole family of different toxins, and we can show that more than one substance is always involved in a staphylococcic infection.”
Scope and Content
The Frank A. Kapral Papers (17 linear feet) contain laboratory notebooks and 35mm slides documenting Kapral’s research. The subject is primarily diseases caused by staphylococcus aureus bacteria.
Statement of Arrangement
This collection is arranged in two series:
- Series I: Lab Books
- Series II: Media
Series I: Lab Books (14 boxes) contains research records kept by Frank A. Kapral and others who are presumably his colleagues and/or students. There are also fourteen dissertations and two theses. Thirteen dissertations and one thesis were authored by researchers whose lab books are also in the collection. This series is arranged in alphabetical order.
Series II: Media (12 boxes) contains 35mm slides that accompany the lab books and primarily depict different kinds of bacteria and toxins. The slides are arranged in their original order.
Restrictions on Access
The collection is open to the public and is available for viewing in the Medical
Heritage Center. Materials do not circulate and must be used in the supervised
reading room. Restrictions, including copyright, may exist and some materials may be
too fragile to photocopy or digitize. The MHC charges for duplication services,
which must be performed by staff.
Preferred Citation
[Identification of item], Frank A. Kapral Papers,
SPEC.202405.KAPRAL, Medical Heritage Center, Health Sciences Library,
The Ohio State University.
Detailed Description of The Collection
Series I: Lab Books
1952-2004
1
1
Anaerobes Notes
2004
1
2
Computation Book: A. Mullarky Book III
May 22, 1962-Feb 1965
1
3
Computation Book: Aidis Hare, No. 1
June 1965-1966
1
4
Computation Book: Carol J. Meyer, No. 2
June 27, 1964-Sept 1965
1
5
Computation Book: Frank A. Kapral - Tissue Culture Research Tuberculin Hypersensitivity, No. 2
Feb 1954-Oct 1957
1
6
Computation Book: Frank Kapral - Class Data and Tissue Culture, No. 1
Aug 1952-Jan 1954
1
7
Computation Book: Grace E. Terry/Carol J. Meyer - Staphylococcal, Vol. II
Dec 7, 1964-Oct 8, 1965
1
8
Computation Book: Grace E. Terry - Staphylococcal, Vol. 1
Dec 10, 1962-Dec 4, 1964
1
9
Computation Book: Kapral - Staphylococcal Research Book II, No. 327
May 11, 1959-March 1961
1
10
Computation Book: Kapral - Staphylococcal Research Book III
March 1961-Nov 1961
1
11
Computation Book: Linda M. Hewitt
Jan 1963-March 1966
1
12
Computation Book: Carol Jeanne Neidl-Meyer and Aidis Hare, No. 4 and 2
1966
1
13
Coop Computation Book: Linda M. Hewitt
April 1966
1
14
D. Purvis Record Book
1966-1968
1
15
Dissertation: Delta Toxin of Staphylococcus Aureus I. Immunogenicity II. Production of a Radiolabeled Toxin III. Hydrophobic Interaction Chromatography by Frederick Nolte
1980
1
16
Dissertation: Effect of Staphylococcus Aureus Delta Toxin on Water and Electrolyte Transport in the Gastrointestinal Tract by Alison Lisl Davis O’Brien
1976
2
1
Dissertation: Factors Determining the Sensitivity of Staphylococcus Aureus to the Bactericidal Lipids Produced by the Host in Focal Lesions by Zhuo Xiong
1994
2
2
Dissertation: Factors Governing the Survival of Staphylococcus Aureus in Peritoneal Abscesses by Earl S. Dye III
1978
2
3
Dissertation: Isolation, Purification, and Characterization of a Proofreading-Deficient DNA Polymerase from Mycoplasma Capricolum, subsp. Capricolum 14 by Melissa Myers
1995
2
4
Dissertation: Mechanism of Resistance to Bactericidal Fatty Acids in Staphylococcus Aureus by Joel E. Mortensen
1983
2
5
Dissertation: Pulmonary Infection of Mice with Staphylococcus Aureus by Thomas DeMaria
1977
2
6
Dissertation: Restoration of Host Resistance to Staphylococcus Aureus by Insulin Therapy and Characterization of Host Response to Coagulase – Negative Staphylococci in Intraperitoneal Infections by James Long
1995
2
7
Dissertation: The Presence of Delta Toxin and Lipase in Murine Intraperitoneal Abscesses Generated by Staphylococcus Aureus by Neal Chamberlain
1985
2
8
Dissertation: The Production of a Bactericidal Monoglyceride in Murine Abscesses that are Generated by Staphylococcus Aureus by Howard Engler
1986
2
9
Dissertation: The Production of Bactericidal Fatty Acids from Glycerides in Staphylococcal Abscesses by Thomas Shryock
1982
2
10
Dissertation: The Production of Bactericidal Lipid Within Staphylococcal Abscesses by Thomas Shryock
1982
2
11
Dissertation: The Survival of Staphylococcus Aureus in Abscesses from Streptozotocin-Induced Diabetic Mice by Kevin Harvey
1990
2
12
Dissertation: The Survival of Staphylococcus Aureus in Renal Abscesses
1981
2
13
F. Nolte Record Book
1980
2
14
Gram-Negative Enteric Bacteria Notes
2004
2
15
Gram Positive Bacteria: The Streptococci Notes
2004
2
16
Graphs IP Abscesses Calculations E. Dye
1976
2
17
Harvey I Record Book
Dec 1984-June 1986
2
18
J. Godwin Record Book
1968-1969
2
19
Jim Long Lab Data
1998
2
20
John Chin Record Book IV
1981
3
1
Jones IV Record Book
1986-1988
3
2
Joyce Mauser Neimark Med. Microbiology Staphylococcal Notebook
1956-1957
3
3
Kapral Record Book
1970
3
4
Margaret Miller Record Book
1970-1972
3
5
Marina G. Kapral Ceramics Book
undated
3
6
Med 1 Integrated Pathway Host Defense Division 1
2003
3
7
Med 1 Integrated Pathway Host Defense Division 1 Lecture Handouts February-March
2003
3
8
Med 1 Integrated Pathway Host Defense Division 2
2003
3
9
Med 1 Integrated Pathway Host Defense Division 2 Lecture Handouts February-March
2003
3
10
Miscellaneous Notes
undated
3
11
MIT Computation Book: Staphylococcal Research I, No 275
Jan 1957-Nov 1959
3
12
Staph Computation Book: Frank A. Kapral Staph. Research, Book II
Nov 1963-July 1966
3
13
T. DeMaria Record Book
1974-1975
3
14
T. DeMaria Record Book IV
1976-1977
3
15
T. Young Record Book
1981
3
16
Thesis: A Comparison of Experimental Staphylococcal Infection in the Pleural and Peritoneal Cavities of Mice by Meriel Ferrell
1973
3
17
Thesis: Growth and Hemolysin Production within Developing Staphylococcal Abscesses by Judy Ricketts Godwin
1969
4
1
Computation Book: Carol J. Meyer
Dec 7, 1962-July 13, 1964
4
2
Record Book: Aidis Hare Book III
Oct 1966-1967
4
3
Record Book: Aidis Hare Book V
1968-1969
4
4
Record Book: D. Purvis
1968
4
5
Record Book: Aidis Arahood Book VII
1969-1970
4
6
Record Book: Susan Heaphy and Aidis Arahood Book VIII
1970-1971
4
7
Record Book: Alison O'Brien Book I
Dec 22, 1972-Nov 6, 1973
5
1
Record Book: Tom DeMaria Book I
1973-1974
5
2
Record Book: P. Hornaday
1973-1974
5
3
Record Book: A. O'Brien Book II
1973-1974
5
4
Record Book: John Chinn Book I
1974-1975
5
5
Record Book: Tom Demaria Book II
1974-1975
5
6
Record Book: E. Dye
1974-1975
5
7
Record Book: P. Hornaday Book II
1974
5
8
Record Book: Alison O'Brien Book III
1974
5
9
Record Book: Alison O'Brien Book IV
1974-1975
6
1
Record Book: John Chinn Book II
1975-1978
6
2
Record Book: Earl Dye
1975-1977
6
3
Record Book: Alison O'Brien Book V
1975
6
4
Record Book: Alison O'Brien Book VI
Aug 17, 1975-Nov 10, 1975
6
5
Record Book: Karen Grandel
1976-1978
6
6
Record Book: Frank A. Kapral
1976-1979
6
7
Record Book: F. Nolte
1976-1978
7
1
Record Book: Alison O'Brien Book VII
1976
7
2
Record Book: Tom Shryock Book I
1976-1979
7
3
Record Book: Earl Dye
1977-1978
7
4
Record Book: John Chinn Book III
1978-1981
7
5
Record Book: Karen Grandel
1978-1980
7
6
Record Book: Kathleen Judge
1978-1980
8
1
Record Book: F. Nolte Book II
1978-1979
8
2
Record Book: F. Nolte Book III
1979-1980
8
3
Record Book: Tom Shryock Book II
1979-1981
8
4
Record Book: Karen Grandel
1980
8
5
Record Book: Karen Grandel
1980-1981
8
6
Record Book: Kathleen Judge
1980-1981
8
7
Record Book: J. Mortensen
1980-1982
9
1
Record Book: Howard Engler Book I
1981-1984
9
2
Record Book: Jones I
1981-1982
9
3
Record Book: Kathleen Judge Book III
1981-1982
9
4
Record Book: Thomas Shryock Book III
1981
9
5
Record Book: Thomas Shryock Book IV
1981-1982
9
6
Record Book: Frances Spray Book I
1981-1983
9
7
Record Book: Neal Chamberlain
1982-1984
9
8
Record Book: Jones II
1982-1983
10
1
Record Book: D. Lal Book I
1982-1983
10
2
Record Book: Joel Mortensen Book II
1982
10
3
Record Book: Joel Mortensen Book III
1982-1983
10
4
Record Book: D. Lal Book II
1983-1984
10
5
Record Book: Frances Spray Book II
1983-1984
10
6
Record Book: Neal Chamberlain
1984-1985
10
7
Record Book: Jones III
1984-1986
10
8
Record Book: Howard Engler Book II
1985-1986
11
1
Record Book: Harvey II
June 1986-Jan 1987
11
2
Record Book: Zhuo Xiong
1986-1989
11
3
Record Book: Harvey III
Jan 1987-Aug 1987
11
4
Record Book: Harvey IV
Aug 1987-Nov 1988
11
5
Record Book: Hart
May 1988
11
6
Record Book: Harvey V
Nov 1988-June 1989
12
1
Record Book: Hart II
Nov 1989-1992
12
2
Record Book: Harvey VI
1989
12
3
Record Book: Jim Long
1989-1994
12
4
Record Book: Hart
1990-1992
12
5
Record Book: Yuhong Liu (Grace) I
1990-1991
12
6
Record Book: Shugang GE
1991-1992
12
7
Record Book: Yuhong Liu (Grace) II
1991-1992
13
1
Record Book: Jim Long
1991-1994
13
2
Record Book: Jim Long
1994-1996
13
3
Record Book: Zhuo Xiong
Feb 1994-Apr 1994
13
4
Record Book: Kapral
May 1995-Jan 1996
13
5
Record Book: Zhuo Xiong – out of order due to irregular size
1989-1992
14
1
Record Book: Zhuo Xiong – out of order due to irregular size
1992-1994
Series II: Media
undated
15
1
G-Rods Diph Legionella HemoP. Bordet Clostridia
undated
15
2
H-P Interact, Norm. Flora Streps Staphs
undated
15
3
Cestodes
undated
15
4
Toxic Shock Syndrome
undated
16
1
Klebsiella, Pseudomonas, Vibrio, Salmonella, Shigella, Mima, Gerontology, Fungi, Spiricca, Genetics, Viruses, Misc.
undated
16
2
Pasteurella, Brucella Mycobact., Anaerobic Inf., Rabies
undated
17
1
IP Abscess, Pulmonary INF, Renal Infection
undated
17
2
Diabetes Studies CNS IP
undated
18
1
Exfolian
undated
18
2
IP Abscess Cidal Lipid
undated
19
1
Untitled
undated
19
2
Fever Iron Reg. Cell Imm. Bacteremia LPS Memb.
undated
20
1
Untitled
undated
20
2
Phago. Inflam. Fever Iron Cell. Imm.
undated
20
3
Meas. Vir. Dose Resp. Surfaces Adhere. BL. Clear.
undated
21
1
Subcutaneous Staph. Infect. In Rabbits Book #1
undated
21
2
Delta Toxin Skins
undated
21
3
Delta Toxin
undated
22
1
Amoebas, Flagellates
undated
22
2
Flagellates, Sporozoa
undated
23
1
Nematodes, Arthropods
undated
23
2
Trematodes
undated
24
1
Enterics Strep. Staph.
undated
24
2
Subcut. INF In Rabbits Suture INF
undated
25
1
Parasites
undated
26
1
HPI Normal Flora
undated
26
2
Clostridia, Listeria, C. Diph, Legionella, H.-Inf.-Bordetella, Anthrax, Meningococcal, Mycobacteria, Misc.
undated