The collection includes examples of Hollander’s graphic design and illustration work and it contains many sketchbooks, idea notebooks and files of original cartoon art and proofs for her pioneering feminst comic strip 'Sylvia'. The papers include examples of her work for organizations and journals and proofs for her anthology collections of ‘Sylvia’ as well as her popular cat books. Also included are copies of reviews and interviews with Hollander about her work. There is personal correspondence, 'Sylvia' fan mail and letters from other cartoonists.

The collection contains Hollander's business correspondence and records associated with the self syndication of ‘Sylvia’ and her work for the greeting cards companies, Maine Line and Recycled Paper Products. The scripts and promotional material for the theatrical production ‘Sylvia’s Real Good Advice’ are here, including the bathrobe used in the show. There is correspondence related to the proposed animation of 'Sylvia' and the collections contains some merchandise and photographs including some of 'Sylvia look alike' events. The papers also include records of Hollander's speaking engagements and albums of 35 mm slides she used in her many presentations.