The Donald E. Lukens Papers, dated 1954-1991 with a bulk of the material dating 1966-1974, contains correspondence, scrapbooks, case files, reports, photographs, awards, bills, political cartoons, requests, pamphlets, and questionnaires regarding Lukens' political career, and to a lesser extent, his personal life. Materials in the collection reflect the multiple roles that Lukens functioned under as a member of the United States House of Representatives and the Ohio Senate. Some materials, such as the bills and subject files, reflect Lukens' role as a legislator as he reviewed political issues and voted on bills. Other materials, such as correspondence, case files and requests from constituents highlight Lukens' role as a public servant. Lukens also engaged in other political activities such as running for office, being a member of the Republican Party and giving speeches at events within his district.

The majority of the collection focuses on Lukens' first term as United States Representative from 1966-1970, and on his time as an Ohio Senator from 1971-1986, with the latter materials focusing mainly on 1973-1974. There are a few scrapbooks that contain news clippings regarding the events that caused Lukens to resign from office, and other files that are about Lukens' 1987-1990 term as a congressman in the United States House of Representatives.

The William B. Saxbe Papers, dated 1962, and 1968-1975 with a bulk of the material dating from 1968-1975, document the public service career of Saxbe as a United States Senator for Ohio from 1968-1974, and as the United States Attorney General from 1974-1975. The collection contains correspondence, military and civilian case files, administrative records, employment files, invitations, requests, and speeches that relate to Saxbe's career, his constituents, and the records compiled by his office. Some of the public policy topics that this collection covers includes transportation, housing, military and veterans issues, governmental operations, and the postal service. The collection possesses numerous files that arrived at the Ohio Congressional Archives with no contents that have been kept in the collection to illustrate the topics encountered by Saxbe's office. While the majority of the collection focuses on Saxbe's Senate career, Series 17: Attorney General's Files, contains files generated while Saxbe was the Attorney General of the United States from 1974-1975.