The collection includes examples of DeCarlo's work, primarily on Archie characters and stories. Other featured characters in the collection include Scooby-Doo, Elvira, and Sabrina the Teenage Witch. The collection primarily consists of prints and photocopies of pages of DeCarlo's work. Other items in the collection include advertising materials, reference pages, photographs, sketchbooks, and sketches.

This collection contains original art and photocopied comics pages and illustrations by Stan Goldberg, as well as the artist's handwritten notes and copies of personal photographs. Correspondence relating to Mr. Goldberg's philanthropic work and from notable people such as Charles Schulz, Mort Walker, Jim Davis, and Stan Lee are housed in the collection's correspondence series. The original artwork series has been separated and is cataloged by the item level in the Billy Ireland Cartoon Library & Museum Art Database.